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dc.contributor.authorBurišková, Klára
dc.contributor.authorRogalewicz, Vladimir
dc.contributor.authorOšťádal, Petr
dc.date.accessioned2019-07-10T08:37:35Z-
dc.date.available2019-07-10T08:37:35Z-
dc.date.issued2019
dc.identifier.citationE+M. Ekonomie a Management = Economics and Management. 2019, roč. 22, č. 1, s. 161-172.cs
dc.identifier.issn2336-5604 (Online)-
dc.identifier.issn1212-3609 (Print)-
dc.identifier.urihttp://hdl.handle.net/11025/34883
dc.format12 s.cs
dc.format.mimetypeapplication/pdf
dc.language.isoenen
dc.publisherTechnická univerzita v Libercics
dc.relation.ispartofseriesE+M. Ekonomie a Management = Economics and Managementcs
dc.rightsCC BY-NC 4.0cs
dc.subjectefektivita nákladůcs
dc.subjectužitečnost nákladůcs
dc.subjectmimotělní kardiopulmonální resuscitacecs
dc.subjectrefrakterní srdeční zástavacs
dc.titleCost-effectiveness of extracorporeal membrane oxygenation in resuscitation of patients with refractory cardiac arresten
dc.typečlánekcs
dc.typearticleen
dc.rights.accessopenAccessen
dc.type.versionpublishedVersionen
dc.description.abstract-translatedExtracorporeal cardiopulmonary resuscitation (ECPR) has been recently introduced as a therapeutic option for refractory cardiac arrest. Despite growing evidence demonstrating improved survival rate, a number of questions remains unanswered and data on cost-effectiveness are still insuffi cient. The paper is based on a retrospective observational comparative study of authentic clinical data from patient records. Incremental cost-effectiveness and cost-utility analyses were performed from health care provider’s perspective. Sixteen patients undergoing ECPR were included into the analysis and their data were compared with 35 subjects with conventional CPR for refractory cardiac arrest. In the ECPR group eight out of sixteen patients were weaned from ECMO, four of them with good neurological outcomes (CPC 1-2); three patients survived one year with CPC 1-2, one patient survived one year with severe neurological dysfunction (CPC 3), and one patient with persisting coma (CPC 4). In comparison, in the non-ECPR group all patients died within 24 hours. In the ECPR group, the average annual costs per patient reached CZK 885,044 (Levitronix Centrimag), and CZK 788,432 (Cardiohelp) (the 2013 price level). CUA revealed 3,961,970 CZK/ QALY with Cardiohelp, and 4,447,457 CZK/QALY with Levitronix. However, if only patients with CPC 1-2 were included into the analysis, the cost-utility ratio decreased below the unoffi cial Czech cost-effectiveness threshold. Our data indicate that ECPR for refractory cardiac arrest may be cost-effective despite high costs per individual patients, especially if we were able to better select patients for this intervention based on a reliable prediction of the neurological outcome.en
dc.subject.translatedcost-effectivenesscs_CZ
dc.subject.translatedcost-utilitycs_CZ
dc.subject.translatedextracorporeal cardiopulmonary resuscitationcs_CZ
dc.subject.translatedrefractory cardiac arrestcs_CZ
dc.identifier.doihttps://dx.doi.org/10.15240/tul/001/2019-2-011
dc.type.statusPeer-revieweden
Appears in Collections:Číslo 2 (2019)
Číslo 2 (2019)

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