Title: Constitutive modelling of an arterial wall supported by microscopic measurements
Authors: Vychytil, Jan
Kochová, Petra
Tonar, Zbyněk
Kuncová, Jitka
Švíglerová, Jitka
Citation: Applied and Computational Mechanics. 2012, vol. 6, no. 1, p. 107-118.
Issue Date: 2012
Publisher: University of West Bohemia
Document type: article
článek
URI: http://www.kme.zcu.cz/acm/index.php/acm/article/view/167/163
http://hdl.handle.net/11025/1312
ISSN: 1802-680X (Print)
2336-1182 (Online)
Keywords: arteriální stěna;hyperelasticita;multiškálové modelování;stereologie
Keywords in different language: arterial wall;hyperelasticity;multi-scale modelling;stereology
Abstract: An idealized model of an arterial wall is proposed as a two-layer system. Distinct mechanical response of each layer is taken into account considering two types of strain energy functions in the hyperelasticity framework. The outer layer, considered as a fibre-reinforced composite, is modelled using the structural model of Holzapfel. The inner layer, on the other hand, is represented by a two-scale model mimicing smooth muscle tissue. For this model, material parameters such as shape, volume fraction and orientation of smooth muscle cells are determined using the microscopic measurements. The resulting model of an arterial ring is stretched axially and loaded with inner pressure to simulate the mechanical response of a porcine arterial segment during inflation and axial stretching. Good agreement of the model prediction with experimental data is promising for further progress.
Rights: © 2012 University of West Bohemia. All rights reserved.
Appears in Collections:Volume 6, number 1 (2012)
Články / Articles (MMI)
Volume 6, number 1 (2012)

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