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DC poleHodnotaJazyk
dc.contributor.authorZeckzer, Dirk
dc.contributor.authorWiegreffe, Daniel
dc.contributor.authorMüller, Lydia
dc.contributor.editorSkala, Václav
dc.date.accessioned2019-05-07T06:16:56Z
dc.date.available2019-05-07T06:16:56Z
dc.date.issued2018
dc.identifier.citationJournal of WSCG. 2018, vol. 26, no. 1, p. 1-10.en
dc.identifier.issn1213-6972 (print)
dc.identifier.issn1213-6980 (CD-ROM)
dc.identifier.issn1213-6964 (on-line)
dc.identifier.uriwscg.zcu.cz/WSCG2018/!_2018_Journal_WSCG-No-1.pdf
dc.identifier.urihttp://hdl.handle.net/11025/34583
dc.format10 s.cs
dc.format.mimetypeapplication/pdf
dc.language.isoenen
dc.publisherVáclav Skala - UNION Agencycs
dc.relation.ispartofseriesJournal of WSCGen
dc.rights© Václav Skala - UNION Agencycs
dc.subjectshlukovánícs
dc.subjectskládánícs
dc.subjectdlaždicecs
dc.subject3D bodový diagramcs
dc.subjectbiologická vizualizacecs
dc.subjectmodifikace histonucs
dc.titleAnalyzing histone modifications using tiled binned clustering and 3D scatter plotsen
dc.typečlánekcs
dc.typearticleen
dc.rights.accessopenAccessen
dc.type.versionpublishedVersionen
dc.description.abstract-translatedA major goal in epigenetics is understanding how cells differentiate into different cell types. Besides the increase of individual data sets, the amount of replicated experiments generating a tremendous amount of data is ever increasing. While biologists primarily analyze their data on the highest level using statistical correlations or on the lowest level analyzing nucleotide sequences, determining the fate of histone modifications during cell specification necessitates improved analysis capabilities on one or more intermediate levels. For this type of analysis, it proved to be very useful to use tiled binned scatter plot matrices showing binary relationships or to use tiled binned 3D scatter plots showing ternary relationships. Quarternary or general n-ary relationships are not easily analyzable using visualization techniques like scatter plots, only. Therefore, we augmented existing clustering methods with the tiling and binning idea enabling the analysis of n-ary relationships. Analyzing the changes of histone modifications comparing two cell lines using tiled binned clustering, we found new, unknown relations in the data.en
dc.subject.translatedclusteringen
dc.subject.translatedbinningen
dc.subject.translatedtilesen
dc.subject.translated3D scatterploten
dc.subject.translatedbiological visualizationen
dc.subject.translatedhistone modificationsen
dc.identifier.doihttps://doi.org/10.24132/JWSCG.2018.26.1.1
dc.type.statusPeer-revieweden
Vyskytuje se v kolekcích:Volume 26, Number 1 (2018)

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  1. DSpace at University of West Bohemia
  2. Publikace ZČU / UWB Publications
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  4. Journal of WSCG
  5. Volume 26 (2018)
  6. Volume 26, Number 1 (2018)