Title: Multiscale modelling of liver perfusion
Authors: Rohan, Eduard
Turjanicová, Jana
Lukeš, Vladimír
Citation: ROHAN, E., TURJANICOVÁ, J., LUKEŠ, V. Multiscale modelling of liver perfusion. In: 15th International Conference on Computational Plasticity. Fundamentals and Applications, COMPLAS 2019. Barcelona: International Center for Numerical Methods in Engineering, 2019. s. 343-353. ISBN 978-84-949194-7-3.
Issue Date: 2019
Publisher: International Center for Numerical Methods in Engineering
Document type: konferenční příspěvek
URI: 2-s2.0-85101984839
ISBN: 978-84-949194-7-3
Keywords in different language: Homogenization;Double Porosity;Liver Tissue;Perfusion;Darcy-Brinkman model
Abstract in different language: We compare two homogenized models of the microcirculation which rely on different assumptions. The first model has been derived by the homogenization of the mesoscopic structure with the double-porosity medium represented by the Biot model with large contrasts in the permeability coefficients constituting the Darcy law. The newly developed so-called Biot-Darcy-Brinkman (BDB) model is described in the paper; it arises from a two-stage homogenization of the fluid-structure interaction problem which requires geometric representations of the sinusoidal and the inter-lobular vasculatures associated with venous compartments, the portal and the hepatic veins. An illustrative example shows a good correspondence between the two models.
Rights: Plný text je přístupný v rámci univerzity přihlášeným uživatelům.
© International Center for Numerical Methods in Engineering
Appears in Collections:Konferenční příspěvky / Conference papers (NTIS)
Konferenční příspěvky / Conference Papers (KME)

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Please use this identifier to cite or link to this item: http://hdl.handle.net/11025/43632

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